Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Stem Cell Therapy for Tissue Regeneration

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Sol-gel derived B<sub>2</sub>O<sub>3</sub>-CaO borate bioactive glasses with hemostatic, antibacterial and pro-angiogenic activities.

Regenerative biomaterials·2024

Same author

Editorial: Bioengineering of biomimetic microenvironments for cardiac tissue engineering.

Frontiers in bioengineering and biotechnology·2023

Same author

The Impact of 45S5-Bioactive Glass on Synovial Cells in Knee Osteoarthritis-An In Vitro Study.

Materials (Basel, Switzerland)·2023

Same author

Bioactive Glass and Silica Particles for Skeletal and Cardiac Muscle Tissue Regeneration.

Tissue engineering. Part B, Reviews·2023

Same author

Surface engineering of mesoporous bioactive glass nanoparticles with bacteriophages for enhanced antibacterial activity.

Colloids and surfaces. B, Biointerfaces·2023

Same author

Mending a broken heart by biomimetic 3D printed natural biomaterial-based cardiac patches: a review.

Frontiers in bioengineering and biotechnology·2023

Search research articles

Related Experiment Video

Updated: May 23, 2026

Integrated Bone Formation Through In Vivo Endochondral Ossification Using Mesenchymal Stem Cells

Integrated Bone Formation Through In Vivo Endochondral Ossification Using Mesenchymal Stem Cells

Published on: July 14, 2023

Osteochondral tissue engineering: scaffolds, stem cells and applications.

Patcharakamon Nooeaid¹, Vehid Salih, Justus P Beier

¹Department of Materials Science and Engineering, Institute of Biomaterials, Friedrich-Alexander-University of Erlangen-Nürnberg, Erlangen, Germany.

Journal of Cellular and Molecular Medicine

|March 29, 2012

Summary

Osteochondral tissue engineering uses composite scaffolds to repair cartilage and bone. This review explores materials, designs, and methods for advanced bilayered scaffolds that mimic natural tissue properties.

More Related Videos

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots

Published on: May 21, 2013

Fabrication of Decellularized Cartilage-derived Matrix Scaffolds

Fabrication of Decellularized Cartilage-derived Matrix Scaffolds

Published on: January 7, 2019

Related Experiment Videos

Last Updated: May 23, 2026

Integrated Bone Formation Through In Vivo Endochondral Ossification Using Mesenchymal Stem Cells

Integrated Bone Formation Through In Vivo Endochondral Ossification Using Mesenchymal Stem Cells

Published on: July 14, 2023

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots

Published on: May 21, 2013

Fabrication of Decellularized Cartilage-derived Matrix Scaffolds

Fabrication of Decellularized Cartilage-derived Matrix Scaffolds

Published on: January 7, 2019

Area of Science:

Biomaterials Science
Regenerative Medicine
Tissue Engineering

Background:

Articular cartilage has limited self-repair capacity, necessitating engineered solutions.
Osteochondral tissue engineering aims to regenerate both cartilage and subchondral bone.
Biodegradable polymers and bioactive ceramics are key components in composite scaffolds.

Purpose of the Study:

To review current osteochondral tissue engineering strategies.
To discuss bilayered composite scaffolds using polymers and ceramics.
To explore scaffold designs, fabrication methods, cell sources, and signaling factors.

Main Methods:

Review of literature on osteochondral tissue engineering.
Analysis of composite scaffold fabrication techniques.
Discussion of cell sourcing and biomolecular incorporation strategies.

Main Results:

Bilayered composite scaffolds combining polymers and ceramics show promise.
Fabrication methods, cell types, and signaling factors significantly impact strategy success.
Scaffold design and material choice are critical for mimicking native tissue.

Conclusions:

Advanced bilayered composite scaffolds can be engineered to regenerate osteochondral defects.
Mimicking native interfacial tissue properties and biological adaptability are key goals.
Future strategies focus on creating next-generation scaffolds for enhanced osteochondral repair.