Genetic polymorphisms of 5-HTT and DAT but not COMT differentially affect verbal and visuospatial working memory

David Zilles1, Jobst Meyer, Thomas Schneider-Axmann

  • 1Department of Psychiatry, Center for Translational Research in Systems Neuroscience and Psychiatry, University Medical Centre, Georg August University, Goettingen, Germany. david.zilles@med.uni-goettingen.de

Summary

Genetic variations in dopamine and serotonin transporters selectively impact distinct working memory functions. Dopamine transporter gene (DAT) affects visuospatial memory, while serotonin transporter gene (5-HTT) influences verbal memory.

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