Related Experiment Video
Updated: May 23, 2026
03:23
Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
Published on: May 10, 2024
[Persistent Eosinophilia--differential diagnosis and work-up]
M Peduzzi1, M Schwitter, R Cathomas
1Departement Innere Medizin, Medizinische Onkologie, Kantonsspital Graubünden, Chur.
Praxis
|March 29, 2012
Summary
Persistent eosinophilia can be challenging to diagnose. This case highlights Strongyloidiasis as a cause, even with negative stool exams, emphasizing serologic testing for accurate diagnosis.
Area of Science:
- Internal Medicine
- Infectious Diseases
- Hematology
Background:
- Eosinophilia presents a broad differential diagnosis, challenging clinicians globally.
- In Western countries, eosinophilia is often linked to atopy or drug reactions, unlike parasitic causes prevalent in developing nations.
Observation:
- A case report of an asymptomatic patient with persistent, marked eosinophilia is presented.
- Initial parasitic stool examinations for Strongyloidiasis were repeatedly negative.
Findings:
- Despite negative stool examinations, serologic testing confirmed Strongyloidiasis as the cause of eosinophilia.
- This underscores the utility of serology in diagnosing parasitic infections when traditional methods fail.
Implications:
- Highlights the importance of considering parasitic infections like Strongyloidiasis in the differential diagnosis of unexplained eosinophilia.
- Suggests that serologic testing is a crucial tool for diagnosing Strongyloidiasis, especially in cases with negative stool results.
- Emphasizes the need for a comprehensive diagnostic approach to eosinophilia, integrating serological methods when indicated.
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