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Related Experiment Video

Updated: May 23, 2026

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis

Published on: May 10, 2024

[Persistent Eosinophilia--differential diagnosis and work-up].

M Peduzzi¹, M Schwitter, R Cathomas

¹Departement Innere Medizin, Medizinische Onkologie, Kantonsspital Graubünden, Chur.

|March 29, 2012

Summary

This summary is machine-generated.

Persistent eosinophilia can be challenging to diagnose. This case highlights Strongyloidiasis as a cause, even with negative stool exams, emphasizing serologic testing for accurate diagnosis.

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Identification and Characterization of Immunogenic RNA Species in HDM Allergens that Modulate Eosinophilic Lung Inflammation

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Published on: May 30, 2020

Area of Science:

Internal Medicine
Infectious Diseases
Hematology

Background:

Eosinophilia presents a broad differential diagnosis, challenging clinicians globally.
In Western countries, eosinophilia is often linked to atopy or drug reactions, unlike parasitic causes prevalent in developing nations.

Observation:

A case report of an asymptomatic patient with persistent, marked eosinophilia is presented.
Initial parasitic stool examinations for Strongyloidiasis were repeatedly negative.

Findings:

Despite negative stool examinations, serologic testing confirmed Strongyloidiasis as the cause of eosinophilia.
This underscores the utility of serology in diagnosing parasitic infections when traditional methods fail.

Implications:

Highlights the importance of considering parasitic infections like Strongyloidiasis in the differential diagnosis of unexplained eosinophilia.
Suggests that serologic testing is a crucial tool for diagnosing Strongyloidiasis, especially in cases with negative stool results.
Emphasizes the need for a comprehensive diagnostic approach to eosinophilia, integrating serological methods when indicated.