Related Experiment Video
Updated: May 23, 2026
07:50
A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
Childhood pars planitis; clinical features and outcomes
Homayoon Nikkhah1, Alireza Ramezani, Hamid Ahmadieh
1Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Journal of Ophthalmic & Vision Research
|March 29, 2012
Summary
Childhood pars planitis, a form of pediatric uveitis, is more common in males and younger children. While complications like endotheliitis occur, visual outcomes are generally favorable with proper treatment.
Area of Science:
- Ophthalmology
- Pediatric uveitis
- Inflammatory eye disease
Background:
- Pars planitis is an idiopathic intermediate uveitis affecting children.
- Understanding its demographic and clinical features is crucial for effective management.
Purpose of the Study:
- To investigate the demographic and clinical characteristics of childhood pars planitis.
- To assess the therapeutic and visual outcomes in pediatric patients diagnosed with this condition.
Main Methods:
- Retrospective review of medical records for pediatric patients (<16 years) with pars planitis.
- Inclusion criteria: diagnosis of pars planitis and a minimum of 6 months follow-up.
- Data collected from Labbafinejad Medical Center, Tehran, Iran, over a 22-year period.
Main Results:
- The study included 117 eyes from 61 pediatric patients (83.6% male), with a mean age of 7.8 years at diagnosis.
- Best corrected visual acuity (BCVA) improved significantly from 0.88 logMAR at presentation to 0.39 logMAR at the final visit (P<0.001).
- Endotheliitis was observed in 19.6% of eyes, more frequently in children younger than 9 years (P=0.025). Cataract (41.9%) and cystoid macular edema (19.7%) were common complications.
Conclusions:
- Childhood pars planitis predominantly affects males and younger children, with endotheliitis potentially indicating inflammation spillover.
- Factors associated with better final visual acuity include better baseline vision, older age at onset, absence of endotheliitis, and female gender.
- The visual prognosis for childhood pars planitis is generally favorable with appropriate therapeutic interventions.
Related Concept Videos
01:20COPD: Pathogenesis and Clinical Features
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
01:22Bacterial Meningitis I: Introduction
Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
01:25Chronic Pancreatitis I: Introduction
Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80% of...
01:24Chronic Pancreatitis I: Introduction
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
01:24Asthma-III: Symptoms and Complications
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
01:13Asthma III: Clinical Manifestations
Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...