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Childhood pars planitis; clinical features and outcomes

Homayoon Nikkhah1, Alireza Ramezani, Hamid Ahmadieh

  • 1Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Journal of Ophthalmic & Vision Research
|March 29, 2012
PubMed

Insights

Childhood pars planitis, a form of pediatric uveitis, is more common in males and younger children. While complications like endotheliitis occur, visual outcomes are generally favorable with proper treatment.

Area of Science:

  • Ophthalmology
  • Pediatric uveitis
  • Inflammatory eye disease

Background:

  • Pars planitis is an idiopathic intermediate uveitis affecting children.
  • Understanding its demographic and clinical features is crucial for effective management.

Purpose of the Study:

  • To investigate the demographic and clinical characteristics of childhood pars planitis.
  • To assess the therapeutic and visual outcomes in pediatric patients diagnosed with this condition.

Main Methods:

  • Retrospective review of medical records for pediatric patients (<16 years) with pars planitis.
  • Inclusion criteria: diagnosis of pars planitis and a minimum of 6 months follow-up.
  • Data collected from Labbafinejad Medical Center, Tehran, Iran, over a 22-year period.

Main Results:

  • The study included 117 eyes from 61 pediatric patients (83.6% male), with a mean age of 7.8 years at diagnosis.
  • Best corrected visual acuity (BCVA) improved significantly from 0.88 logMAR at presentation to 0.39 logMAR at the final visit (P<0.001).
  • Endotheliitis was observed in 19.6% of eyes, more frequently in children younger than 9 years (P=0.025). Cataract (41.9%) and cystoid macular edema (19.7%) were common complications.

Conclusions:

  • Childhood pars planitis predominantly affects males and younger children, with endotheliitis potentially indicating inflammation spillover.
  • Factors associated with better final visual acuity include better baseline vision, older age at onset, absence of endotheliitis, and female gender.
  • The visual prognosis for childhood pars planitis is generally favorable with appropriate therapeutic interventions.
Abstract

Keywords:
Childhood UveitisComplicationsPars PlanitisVisual Outcome

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