Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Primary Lymphoid Organs

Primary Lymphoid Organs

Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...

Secondary Lymphoid Organs

Secondary Lymphoid Organs

Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Early clinical outcomes of keratoplasty using donor corneas preserved in sinasol (ZiSol) versus optisol-GS.

Cell and tissue banking·2026

Same author

Effect of Ma'aljobon (Whey) Consumption on Functional Constipation in Older Adults: A Randomized Double-Blind Controlled Trial.

Health science reports·2026

Same author

Ocular Safety of Intravitreal Engineered Humanized Anti-VEGF Nanobody and Its Efficacy in the Attenuation of Choroidal Neovascularization and Associated Subretinal Fibrosis.

Biomolecules·2026

Same author

Epithelial cell proliferation on anterior surface of intraocular lens after Descemet stripping automated endothelial keratoplasty (DSAEK) surgery: a case report.

BMC ophthalmology·2026

Same author

Investigating spiritual health and social well-being and its relationship with the attitude towards childbearing among nurses.

BMC pregnancy and childbirth·2026

Same author

Investigating spiritual well-being and its relationship with health behaviors, depression, and academic achievement in medical students: a structural equation modeling study.

BMC psychology·2026

Search research articles

Related Experiment Video

Updated: May 23, 2026

Cell-Free DNA Extraction of Vitreous and Aqueous Humor Specimens for Diagnosis and Monitoring of Vitreoretinal Lymphoma

Cell-Free DNA Extraction of Vitreous and Aqueous Humor Specimens for Diagnosis and Monitoring of Vitreoretinal Lymphoma

Published on: January 12, 2024

Bilateral primary intraocular lymphoma.

Mehrdad Karimi¹, Masoud Soheilian, Mozhgan Rezaei Kanavi

¹Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Journal of Ophthalmic & Vision Research

|March 29, 2012

Summary

Primary intraocular lymphoma can affect young adults, presenting as chronic panuveitis. Prompt diagnosis via vitrectomy and treatment with intravitreal methotrexate led to a favorable outcome in this case.

Keywords:

B-cell Lymphoma Primary Intraocular Lymphoma

More Related Videos

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Related Experiment Videos

Last Updated: May 23, 2026

Cell-Free DNA Extraction of Vitreous and Aqueous Humor Specimens for Diagnosis and Monitoring of Vitreoretinal Lymphoma

Cell-Free DNA Extraction of Vitreous and Aqueous Humor Specimens for Diagnosis and Monitoring of Vitreoretinal Lymphoma

Published on: January 12, 2024

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Area of Science:

Ophthalmology
Hematology
Oncology

Background:

Primary intraocular lymphoma (IOL) is a rare extranodal non-Hodgkin lymphoma.
It often presents as a chronic, treatment-resistant panuveitis, mimicking other inflammatory conditions.

Observation:

A 33-year-old male presented with a two-year history of bilateral blurred vision.
Ocular examination revealed significant findings including keratic precipitates, anterior chamber reaction, posterior subcapsular cataracts, and vitreous infiltration.

Findings:

Diagnostic 25-gauge pars plana vitrectomy with cytologic evaluation confirmed intraocular lymphoma.
The patient received intravitreal methotrexate for both eyes, resulting in a positive clinical response.
Central nervous system evaluation for systemic lymphoma was negative.

Implications:

This case highlights the importance of considering primary intraocular lymphoma in young adults with chronic, recalcitrant panuveitis.
Early diagnosis and targeted treatment, such as intravitreal methotrexate, can lead to favorable visual outcomes.
Further research into the diagnostic and therapeutic strategies for IOL is warranted.