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Updated: May 23, 2026

Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation

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Published on: September 11, 2012

Methamphetamine-induced paralytic ileus.

Terri L Carlson¹, Timothy P Plackett, Ronald A Gagliano

¹Department of Surgery, Tripler Army Medical Center, Honolulu, HI, USA.

Hawai'I Journal of Medicine & Public Health : a Journal of Asia Pacific Medicine & Public Health

|March 29, 2012

Summary

This summary is machine-generated.

Methamphetamine use can cause paralytic ileus, a rare intestinal obstruction. This case highlights a new gastrointestinal complication of stimulant abuse.

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Gastrointestinal Motility Monitor (GIMM)

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Area of Science:

Gastroenterology
Toxicology
Cardiology

Background:

Methamphetamine abuse is a significant public health issue in the US.
Methamphetamine is a stimulant affecting monoamine neurotransmitters.
Cardiovascular effects like tachycardia and hypertension are well-documented.

Observation:

A patient presented with chest and abdominal pain post-methamphetamine use.
Initial symptoms suggested cardiovascular distress.
Gastrointestinal complications were investigated.

Findings:

The patient was diagnosed with paralytic ileus.
This is the first reported case of methamphetamine-induced paralytic ileus.
Methamphetamine can cause non-cardiovascular complications.

Implications:

Clinicians should consider paralytic ileus in patients with abdominal pain after methamphetamine use.
This finding expands the known spectrum of methamphetamine toxicity.
Further research into the mechanisms of methamphetamine-induced gastrointestinal dysfunction is warranted.