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Dynamic Clamp Methods to Investigate Impaired Neuronal Excitability Associated with Autism
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Published on: October 17, 2025

Rapunzel syndrome.

Eitezaz Ahmed Bashir1, Samiullah, Muhammad Attique Sadiq

  • 1Department of Surgery, Foundation University Medical College, Islamabad, Pakistan. eitezazbashir@hotmail.com

Journal of Ayub Medical College, Abbottabad : JAMC
|March 30, 2012
PubMed
Summary
This summary is machine-generated.

Rapunzel syndrome, a rare condition involving a bezoar extending through the gastrointestinal tract, was diagnosed in an 8-year-old girl. Surgical removal of the large trichobezoar from her stomach and small intestine was successful.

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Area of Science:

  • Pediatric Gastroenterology
  • Surgical Case Reports

Background:

  • Bezoars are indigestible masses in the gastrointestinal tract, with trichobezoars (hair concretions) being common in children.
  • Rapunzel syndrome is an extremely rare variant where a bezoar extends from the stomach into the small intestine.

Observation:

  • An 8-year-old girl presented with chronic, vague abdominal pain and epigastric fullness lasting one year.
  • Investigations revealed a significant trichobezoar.
  • Surgical exploration (laparotomy) identified a large, foul-smelling trichobezoar occupying the stomach, duodenum, and proximal jejunum.

Findings:

  • The patient was diagnosed with Rapunzel syndrome, characterized by a gastric and intestinal trichobezoar.
  • The trichobezoar was successfully removed via gastrostomy.

Implications:

  • This case highlights the importance of considering rare gastrointestinal conditions like Rapunzel syndrome in pediatric patients with persistent abdominal symptoms.
  • Early diagnosis and surgical intervention are crucial for managing large trichobezoars and preventing complications.