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Related Experiment Video

Updated: May 23, 2026

The Establishment of a Murine Maxillary Orthodontic Model

The Establishment of a Murine Maxillary Orthodontic Model

Published on: October 27, 2023

[Cervical vertebrae: Mandibular growth dynamism indicators?].

Monique Raberin¹, Ilinca Cozor, Stéphanie Gobert-Jacquart

¹142, avenue des Frères Lumière, 69008 Lyon, France - Faculté d'Odontologie, rue Guillaume Paradin, 69008 Lyon, France.

L' Orthodontie Francaise

|March 30, 2012

Summary

This study found significant correlations between skeletal maturation indicators and cervical vertebrae maturation stages. Mandibular growth increases notably between stages CVS 4 and CVS 5, informing optimal orthodontic treatment timing.

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Last Updated: May 23, 2026

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Area of Science:

Orthodontics
Growth and Development
Skeletal Biology

Background:

Assessing skeletal maturation is crucial for determining optimal timing for orthodontic interventions in Class II discrepancies.
Cervical vertebrae maturation (CVS) and hand-wrist maturation are commonly used indicators of skeletal maturity.

Purpose of the Study:

To investigate the relationship between different skeletal maturation indices and cervical vertebrae maturation stages.
To identify specific maturation stages associated with significant mandibular growth.
To provide guidance for optimizing orthodontic treatment timing based on maturation indicators.

Main Methods:

A retrospective longitudinal study of 103 patients (69 girls, 34 boys) aged 11–16 years with Class II skeletal discrepancy.
Correlation analysis between Björk stages (MP3=, MP3 cap, MP3 U) and Lamparski's cervical vertebrae maturation stages (CVS 2–6).
Evaluation of mandibular growth changes in relation to identified maturation stages.

Main Results:

Significant correlations were observed between Björk stages and Lamparski stages (CVS 2, CVS 3–4, CVS 5–6).
A notable increase in mandibular length was identified between CVS 4 and CVS 5.
Mandibular growth appears to continue beyond the MP3 U stage or CVS 5 stage.

Conclusions:

Cervical vertebrae maturation stages correlate significantly with specific skeletal maturation indicators.
The period between CVS 4 and CVS 5 represents a phase of substantial mandibular growth, suggesting responsiveness to stimulation.
These findings help refine the timing of orthodontic therapy for improved outcomes in patients with Class II discrepancies.