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Updated: May 23, 2026

Measuring Neural and Behavioral Activity During Ongoing Computerized Social Interactions: An Examination of Event-Related Brain Potentials
Published on: November 15, 2014
The implications of social neuroscience for social disability
James C McPartland1, Kevin A Pelphrey
1Yale Child Study Center, 230 South Frontage Road, New Haven, CT 06520, USA. james.mcpartland@yale.edu
Abstract:
Social disability represents a unifying feature in the diverse group of individuals with autism spectrum disorder (ASD). Social neuroscience is the study of brain mechanisms supporting interpersonal interaction. In this paper, we review brain imaging studies of the social brain and highlight practical applications of these scientific insights. Understanding of social brain mechanisms holds promise as a tool for defining meaningful subgroups of children with ASD to facilitate genetic analyses and to inform treatment selection. Because social brain systems emerge in infancy, social neuroscience may help to detect atypical development before symptoms manifest. This conceptualization of ASD is a hopeful one, as social brain systems remain malleable well into development and are thus amenable to targeted intervention.
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