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Updated: May 23, 2026

A Murine Model of Pressure Overload-Induced Right Ventricular Hypertrophy and Failure by Pulmonary Trunk Banding
Published on: June 14, 2024
Mid-term results after correction of type I and type II persistent truncus arteriosus in older patients
Yan Zhang1, Shou-jun Li, Jun Yan
1Department of Cardiovascular Surgery, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Objective:
This study aims to analyze long-term results after correction of type I and type II truncus arteriosus in older patients operated in one institution over five years.
Methods:
Between 2006 and 2010, 12 patients, median age 4 years, underwent repair of truncus arteriosus. Repair with reconstruction of the right ventricular to pulmonary artery continuity was performed using a valved conduit in 12 patients.
Results:
There was no early mortality. All patients are alive with their original conduit 0.6 to 5 years after correction. No patients required reoperations for conduit dysfunction. Recent clinical examination was undertaken in all patients and they are in good condition.
Conclusions:
Though mean age at operation was higher in this study than published results, the operation should be performed if the pulmonary vascular resistance is under 8 units.m(2) before operation.
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