Human parvovirus PARV4 in plasma pools of Chinese origin
1Laboratory for Viral Safety of National Centre of Biomedical Analysis, Institute of Transfusion Medicine, Academy of Military Medical Sciences, Beijing, China.
Vox Sanguinis
|March 31, 2012
Abstract:
Human parvovirus 4 (PARV4) is present in blood and blood products. As the presence and levels of PARV4 in Chinese source plasma pools have never been determined, we implemented real-time quantitative PCR to investigate the presence of PARV4 in source plasma pools in China. Results showed that 26·15% (51/195) of lots tested positive for PARV4. The amounts of DNA ranged from 2·83 × 10(3) copies/ml to 2·35×10(7) copies/ml plasma. The high level of PARV4 in plasma pools may pose a potential risk to recipients. Further studies on the pathogenesis of PARV4 are urgently required.
