Homocysteine predicts increased NT-pro-BNP through impaired fatty acid oxidation

R M Guéant Rodriguez1, R Spada, S Pooya

  • 1INSERM U954, Medical Faculty and CHU of Nancy, University Henri Poincaré, Nancy, France. rm.rodriguez@chu-nancy.fr

Summary

Methyl donor deficiency, like folate, increases homocysteine, impairing heart mitochondrial fatty acid oxidation and raising NT-pro-BNP levels. This highlights a key link between homocysteine and heart disease biomarkers.

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