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Related Experiment Video

Updated: May 23, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
06:15

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Primary orbital pleomorphic liposarcoma: an aggressive course.

Sun Young Jang1, Su Yan Zhao, Jin Hyung Kim

  • 1Department of Ophthalmology, The Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea.

Ophthalmic Plastic and Reconstructive Surgery
|March 31, 2012
PubMed
Summary
This summary is machine-generated.

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This case study highlights an aggressive orbital pleomorphic liposarcoma with rapid brain invasion and multiple recurrences. High-grade histology and prior surgery may contribute to poor outcomes in this rare orbital tumor.

Area of Science:

  • Ophthalmology
  • Oncology
  • Pathology

Background:

  • Orbital pleomorphic liposarcoma is a rare malignant tumor.
  • Aggressive presentations and poor prognoses are infrequently reported.

Observation:

  • A 59-year-old man presented with orbital pleomorphic liposarcoma.
  • The patient experienced multiple local recurrences and died within one year of diagnosis.
  • Tumor invasion into the brain occurred 10 months post-exenteration.

Findings:

  • Histologic examination revealed a high-grade pleomorphic liposarcoma with a high mitotic count (25/10 HPF).
  • Prior anterior orbitotomy for partial tumor resection may have contributed to tumor seeding.

Implications:

Related Experiment Videos

Last Updated: May 23, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
06:15

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

  • This case underscores the potential for aggressive behavior in orbital pleomorphic liposarcoma.
  • High-grade histology and surgical history are critical factors influencing patient outcomes.