Related Experiment Video
Updated: May 23, 2026
07:16
DNAzyme 10-23 - Based Nanomachines for Nucleic Acid Recognition
Published on: February 9, 2024
Ultrasensitive colorimetric DNA detection using a combination of rolling circle amplification and nicking
1Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543.
Small (Weinheim an Der Bergstrasse, Germany)
|March 31, 2012
Abstract:
A combination of rolling circle amplification and nicking endonuclease-assisted nanoparticle amplification (NEANA) is used for the rapid, colorimetric detection of DNA. The integration of rolling circle amplification into the NEANA approach allows for detection of oligonucleotides with arbitrary sequences at ultralow concentrations.
