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hnRNP C tetramer measures RNA length to classify RNA polymerase II transcripts for export

Asako McCloskey1, Ichiro Taniguchi, Kaori Shinmyozu

  • 1Institute for Virus Research, Kyoto University, Kyoto, Japan.

Science (New York, N.Y.)
|March 31, 2012
PubMed
Summary

Heterogeneous nuclear ribonucleoprotein (hnRNP) C1/C2 tetramers act as molecular rulers, classifying RNA polymerase II transcripts by length. This mechanism sorts transcripts for export as messenger RNA or U snRNA based on size.

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