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Applying what we know to accelerate cancer prevention
Graham A Colditz1, Kathleen Y Wolin, Sarah Gehlert
1Alvin J. Siteman Cancer Center and Division of Public Health Sciences, Department of Surgery, Washington University, St. Louis, MO 63110, USA. colditzg@wudosis.wustl.edu
Science Translational Medicine
|March 31, 2012
Summary
Most cancer is preventable through lifestyle changes like avoiding tobacco and obesity. Implementing known prevention strategies requires societal commitment and better research infrastructure.
Area of Science:
- Oncology
- Preventive Medicine
- Public Health
Background:
- Over 50% of current cancer cases are preventable with existing knowledge.
- Tobacco use, obesity, and physical inactivity are leading modifiable causes of cancer burden.
Purpose of the Study:
- To highlight the potential for cancer prevention through behavior modification and public health initiatives.
- To identify obstacles hindering the implementation of known cancer prevention strategies.
Main Methods:
- Review of existing scientific knowledge on cancer etiology and prevention.
- Analysis of societal and institutional barriers to implementing preventive measures.
Main Results:
- Significant cancer burden is attributable to modifiable lifestyle factors.
- Societal and institutional factors, including academic structures and daily habits, impede prevention efforts.
Conclusions:
- Effective cancer prevention requires translating existing knowledge into action through behavioral and public health changes.
- Enhanced infrastructure is needed to support transdisciplinary research and interventions for maximal cancer prevention.
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