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Gavage Strategy for Decoction Formula of Traditional Chinese Medicine in Osteosarcoma Model Mice
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"Toxic" beef bone soup.

Kamal Kishore Pandita1, Sarla Pandita, Tanveer Hassan

  • 1Associate professor, Department of Medicine Acharya Shri Chander College of Medical Sciences, Sidhra Jammu J&k State India.

Clinical Cases in Mineral and Bone Metabolism : the Official Journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases
|March 31, 2012
PubMed
Summary

Excessive consumption of bone broth led to hypercalcaemia and hypervitaminosis D in a young athlete. This case underscores the importance of detailed dietary assessments for diagnosing metabolic disorders.

Keywords:
dietary historyhypercalcaemiahypervitaminosis D

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Area of Science:

  • Endocrinology
  • Nutritional Science
  • Internal Medicine

Background:

  • Hypercalcaemia is commonly linked to primary hyperparathyroidism or malignancy.
  • Vitamin D intoxication, a cause of hypercalcaemia, often results from excessive vitamin D supplementation or fortified foods.

Observation:

  • A young cricketer presented with recurrent vomiting attributed to hypercalcaemia and hypervitaminosis D.
  • The patient habitually consumed large volumes of soup made from boiled beef bones over an extended period.

Findings:

  • The patient's excessive intake of homemade bone broth was identified as the likely source of hypervitaminosis D.
  • This led to severe hypercalcaemia, manifesting as recurrent vomiting.

Implications:

  • Highlights a non-traditional source of vitamin D toxicity beyond supplements and fortified foods.
  • Emphasizes the critical role of comprehensive dietary history in diagnosing complex metabolic conditions like hypercalcaemia.