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Updated: May 23, 2026

Optogenetic Inhibition of Rho1-Mediated Actomyosin Contractility Coupled with Measurement of Epithelial Tension in Drosophila Embryos
12:35

Optogenetic Inhibition of Rho1-Mediated Actomyosin Contractility Coupled with Measurement of Epithelial Tension in Drosophila Embryos

Published on: April 14, 2023

ROCK1 and ROCK2 regulate epithelial polarisation and geometric cell shape.

Ruba Kalaji1, Ann P Wheeler, Jennifer C Erasmus

  • 1Faculty of Medicine, Molecular Medicine Section, National Heart and Lung Institute, Imperial College of London, London, UK.

Biology of the Cell
|April 3, 2012
PubMed
Summary

ROCK proteins regulate myosin II contraction, influencing epithelial cell shape and polarity during differentiation. This study clarifies their role in cell elongation and geometric shape acquisition.

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