Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Experience in examining infectious hepatitis patients by using a viral detection method].

S S Savinskaia, A G Andraparidze, M S Balaian

    Zhurnal Mikrobiologii, Epidemiologii I Immunobiologii
    |July 1, 1979
    PubMed
    Summary

    Immune electron microscopy effectively detects hepatitis A virus (HAV) in patient stools, even late in infectious hepatitis. This diagnostic method reveals prolonged virus shedding, highlighting potential transmission risks from both typical and anicteric cases.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Inadvertent administration of magnesium sulfate through the epidural catheter: report and analysis of a drug error.

    International journal of obstetric anesthesia·2005
    Same author

    [Propagation of hepatitis E virus in an endemic and nonendemic regions].

    Voprosy virusologii·2002
    Same author

    [Study of hepatitis E virus replication in FRhK-4 cell culture].

    Voprosy virusologii·1997
    Same author

    [Hepatitis E in a nonendemic region: antibodies to hepatitis E virus in various groups of residents].

    Voprosy virusologii·1996
    Same author

    Doxacurium vs. Pancuronium.

    Critical care medicine·1996
    Same author

    Anaesthesia drug cost, control and utilization in Canada.

    Canadian journal of anaesthesia = Journal canadien d'anesthesie·1996

    Area of Science:

    • Virology
    • Immunology
    • Pediatrics

    Context:

    • Hepatitis A virus (HAV) infection is a significant public health concern, particularly in pediatric populations.
    • Accurate and timely diagnosis is crucial for managing infectious hepatitis and preventing its spread.
    • Understanding the duration and patterns of viral shedding is essential for epidemiological control.

    Purpose:

    • To evaluate the efficacy of immune electron microscopy (IEM) as a diagnostic tool for detecting HAV in stools.
    • To determine the rate and duration of HAV shedding in children with infectious hepatitis.
    • To investigate the relationship between viral shedding, disease presentation, and immune response.

    Summary:

    • Immune electron microscopy (IEM) successfully detected hepatitis A virus (HAV) particles in the stools of children with infectious hepatitis, even in later disease stages.

    Related Experiment Videos

  • A 10.5% positive detection rate was observed in 225 children, with shedding lasting approximately two weeks post-onset.
  • Both typical and anicteric forms of hepatitis A were associated with virus shedding, independent of delayed IgM response.
  • HAV particles identified were antigenically similar to strains found internationally.

    • Impact:

    • IEM is a viable diagnostic method for identifying HAV in infectious hepatitis cases.
    • Findings underscore the potential for prolonged virus shedding, emphasizing the need for continued vigilance in preventing transmission.
    • The study contributes to understanding the clinical and epidemiological characteristics of hepatitis A in children.