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Why does my patient have thrombocytosis?

Nanna H Sulai1, Ayalew Tefferi

  • 1Department of Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

Hematology/Oncology Clinics of North America
|April 3, 2012
PubMed

Thrombocytosis is a common clinical problem frequently encountered during routine evaluation. The diagnostic workup entails a step-by-step approach, which allows for an accurate assessment of the underlying cause. A thorough clinical history and physical examination may help differentiate thrombocytosis secondary to a reactive process versus an underlying clonal proliferation process. Once essential thrombocytosis is evident, relevant laboratory evaluation for an ongoing myeloproliferative disorder is paramount. Various treatment modalities have been proven to be beneficial. With further scientific investigation underway, molecular therapies may soon be cornerstones of therapy in essential thrombocytosis.

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