[Occurrence of severe cardiac alterations in Amanita proxima poisoning: two original observations]

A Besancon1, C Schmitt, M Glaizal

  • 1Service de réanimation polyvalente, centre hospitalier intercommunal, 83608 Fréjus-Saint-Raphaël, France.

Insights

Amanita proxima mushroom poisoning, known as proximien syndrome, can cause severe cardiac issues. Early cardiac evaluation is recommended for patients experiencing this mushroom toxicity.

Area of Science:

  • Toxicology
  • Cardiology
  • Mycology

Background:

  • Amanita proxima mushroom poisoning, termed 'proximien' syndrome in France, is typically associated with digestive issues, mild liver damage, and later kidney problems.
  • Cardiac involvement has not been previously documented in cases of Amanita proxima poisoning.

Observation:

  • Two cases of poisoning from white mushrooms on the French Mediterranean coast presented with classic proximien syndrome symptoms.
  • These patients also developed severe cardiac alterations secondary to the mushroom ingestion.

Findings:

  • The described cases highlight a previously unreported cardiac toxicity associated with Amanita proxima.
  • Both patients recovered fully with symptomatic treatment, indicating potential reversibility of cardiac effects.

Implications:

  • Amanita proxima may possess significant cardiotoxic potential.
  • Early and thorough cardiac assessment should be integrated into the clinical management of patients with suspected Amanita proxima poisoning.

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