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[Occurrence of severe cardiac alterations in Amanita proxima poisoning: two original observations]
A Besancon1, C Schmitt, M Glaizal
1Service de réanimation polyvalente, centre hospitalier intercommunal, 83608 Fréjus-Saint-Raphaël, France.
Abstract:
Amanita proxima is one species of white mushroom which can induce poisonings called in France "proximien" syndrome. The clinical feature of "proximien" syndrome is mainly characterized by early digestive troubles, mild hepatic cytolysis and late renal impairment. A cardiac insult has never been reported in such a circumstance. The authors describe herein two cases of white mushroom poisoning occurred in the Mediterranean French coast with a typical clinical feature of "proximien" syndrome plus secondary development of severe cardiac alterations. The outcome was good for the two patients thanks to symptomatic treatment. The cases reported here suggest that A. proxima have a potential severe cardiac toxicity leading to include early and precise cardiac examination in the management of patients poisoned by these mushrooms.
Insights
Amanita proxima mushroom poisoning, known as proximien syndrome, can cause severe cardiac issues. Early cardiac evaluation is recommended for patients experiencing this mushroom toxicity.
Area of Science:
- Toxicology
- Cardiology
- Mycology
Background:
- Amanita proxima mushroom poisoning, termed 'proximien' syndrome in France, is typically associated with digestive issues, mild liver damage, and later kidney problems.
- Cardiac involvement has not been previously documented in cases of Amanita proxima poisoning.
Observation:
- Two cases of poisoning from white mushrooms on the French Mediterranean coast presented with classic proximien syndrome symptoms.
- These patients also developed severe cardiac alterations secondary to the mushroom ingestion.
Findings:
- The described cases highlight a previously unreported cardiac toxicity associated with Amanita proxima.
- Both patients recovered fully with symptomatic treatment, indicating potential reversibility of cardiac effects.
Implications:
- Amanita proxima may possess significant cardiotoxic potential.
- Early and thorough cardiac assessment should be integrated into the clinical management of patients with suspected Amanita proxima poisoning.
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