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Updated: May 23, 2026

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
Published on: September 25, 2009
Ruptured giant middle cerebral artery aneurysm in infancy
Reem A Al-Youbi1, Mohammed S Binmahfoodh, Hayat Z Kamfar
1Department of Pediatrics, King Abdul-Aziz University, Jeddah, Kingdom of Saudi Arabia.
Insights
Ruptured giant intracranial aneurysms are rare in infants. Prompt neurosurgical intervention in infants with acute raised intracranial pressure can lead to favorable outcomes.
Area of Science:
- Neurology
- Pediatric Neurosurgery
Background:
- Intracranial aneurysms are rare in children, with ruptured giant aneurysms being exceptionally uncommon in infants.
- Infants presenting with acute neurological deterioration require urgent diagnosis and management.
Observation:
- A case of an 11-month-old female infant with a ruptured giant middle cerebral artery aneurysm presenting with unresponsiveness and seizures.
- Urgent craniotomy was performed for aneurysm clipping and hematoma evacuation.
Findings:
- The infant experienced a slow recovery with residual right-sided weakness.
- Follow-up angiography confirmed no residual aneurysm, but the child developed motor delay and recurrent seizures.
- Physiotherapy enabled independent walking by age 3.
Implications:
- Intracranial aneurysms should be considered in the differential diagnosis for infants with acute raised intracranial pressure.
- Prompt management in specialized neurosurgical centers is crucial for improving outcomes in pediatric patients with ruptured intracranial aneurysms.
Abstract:
Intracranial aneurysms are uncommon in children. Rupture of giant intracranial aneurysms is extremely uncommon in infants even in autopsy studies. In this report, we present an unusual case of ruptured giant middle cerebral artery aneurysm in an 11-month-old female infant who presented acutely with unresponsiveness and seizures. The aneurysm was clipped during an urgent craniotomy for evacuation of an associated hematoma. She recovered slowly with mild residual right-sided weakness. Follow up arterial angiography revealed no residual or other aneurysms. Further follow up revealed motor delay and recurrent partial seizures. Active physiotherapy was performed and she could walk independently by 3 years of age. We conclude that intracranial aneurysms have to be considered in the differential diagnosis of infants presenting with acute raised intracranial pressure. Favorable outcome is noted in children who are managed promptly in hospitals with neurosurgical units.
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