Related Experiment Video
Updated: May 23, 2026
Phenol Red Thread-based Sampling Procedure for Untargeted Tear Fluid Lipidomics in Biomarker Discovery
Published on: December 12, 2025
Future directions in non-invasive measurements of tear film surface kinetics
Dorota H Szczesna-Iskander1, D Robert Iskander
1Institute of Physics, Wroclaw University of Technology, Wroclaw, Poland.
Purpose:
To review the methods for dynamic, non-invasive, and objective assessment of tear film surface quality and to outline their current state-of-the-art and their future potential.
Methods:
Among the methods available, high-speed videokeratoscopy, lateral shearing interferometry, and dynamic wavefront sensing are being considered.
Results:
The principles of operations, their advantages and disadvantages, and limitations of each method are being outlined. The possible future directions of each method are also discussed.
Conclusions:
To gain a better understanding of tear film, its structure and function, it is essential to combine macroimaging technologies with those focusing on tear film microstructure. In this way, one can envisage a clinical device that could help, in future, early diagnosis of dry eye syndrome and development of better materials for contact lenses and eye lubricants.
