Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

MRI-Only Simulation for Prostate MRI-Guided SBRT.

Practical radiation oncology·2026
Same author

Are We Treating More Than Pain? Restless Legs Syndrome Outcomes After Lumbar Laminectomy for Radiculopathy.

Neurosurgery·2026
Same author

Nutritional status and outcomes throughout the intestinal transplant journey: Experience from the Cambridge Intestinal Transplant Unit.

Intestinal Failure (New York, N.Y.)·2026
Same author

Mycotic Aneurysms in Intestinal Transplantation: A Case Series.

Clinical transplantation·2026
Same author

The neuroplasticity-based model (NBM): an updated neurorehabilitation model that emphasizes evidence-informed strategies to induce neuroplastic changes.

Disability and rehabilitation·2026
Same author

Normothermic Regional Perfusion Enables Successful Simultaneous Liver-Kidney Transplantation From DCD Donors: A Preliminary Experience.

Clinical transplantation·2026

Related Experiment Video

Updated: May 23, 2026

A Standardized Protocol for Functional Motor Mapping Using Navigated Transcranial Magnetic Stimulation
10:27

A Standardized Protocol for Functional Motor Mapping Using Navigated Transcranial Magnetic Stimulation

Published on: February 27, 2026

Motor map reliability and aging: a TMS/fMRI study.

Keith M McGregor1, Haley Carpenter, Erin Kleim

  • 1Department of Veterans Affairs Rehabilitation Research and Development Brain Rehabilitation Research Center, Malcom Randall VA Medical Center, Gainesville, FL, USA. kmcgrego@phhp.ufl.edu

Experimental Brain Research
|April 3, 2012
PubMed
Summary

Younger adults exhibit more reliable motor maps using transcranial magnetic stimulation (TMS) and functional magnetic resonance imaging (fMRI). Motor map stability differs between age groups, impacting interpretations in older populations.

More Related Videos

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
09:01

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance

Published on: May 7, 2014

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

Related Experiment Videos

Last Updated: May 23, 2026

A Standardized Protocol for Functional Motor Mapping Using Navigated Transcranial Magnetic Stimulation
10:27

A Standardized Protocol for Functional Motor Mapping Using Navigated Transcranial Magnetic Stimulation

Published on: February 27, 2026

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
09:01

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance

Published on: May 7, 2014

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

Area of Science:

  • Neuroscience
  • Neuroimaging
  • Motor Control

Background:

  • Cortical motor maps are crucial for understanding motor control and plasticity.
  • Assessing the reliability of motor maps is essential for clinical and research applications.
  • Age-related differences in neural function may affect the reliability of neuroimaging and stimulation techniques.

Purpose of the Study:

  • To compare the intersession reliability of motor maps derived from neuronavigated transcranial magnetic stimulation (TMS) and functional magnetic resonance imaging (fMRI).
  • To investigate age-related differences in motor map reliability between younger and older adults.
  • To examine the consistency and correlation between TMS and fMRI motor maps.

Main Methods:

  • Three joint TMS/fMRI assessment sessions were conducted on seven younger (19-31 years) and seven older (64-76 years) adults.
  • Motor maps of the right first dorsal interosseous muscle were generated using single-pulse TMS and block-design fMRI during a finger-thumb squeeze task.
  • Intersession reliability was quantified using intraclass correlation and Jaccard Coefficient.

Main Results:

  • Motor maps showed higher intersession reliability in younger adults compared to older adults for both fMRI and TMS.
  • A positive correlation was observed between fMRI and TMS map volumes and spatial consistency across sessions.
  • Both fMRI and TMS demonstrated consistent and complementary information regarding the cortical representation of the first dorsal interosseous muscle.

Conclusions:

  • Younger adults exhibit more stable motor maps, suggesting age-related variability in neurophysiological mapping techniques.
  • Functional magnetic resonance imaging and transcranial magnetic stimulation provide consistent and complementary data on motor cortical representations.
  • Future research and clinical interpretations of motor maps should consider potential age-related differences in reliability.