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Related Concept Videos

Hormonal Control of the Ovarian Cycle01:30

Hormonal Control of the Ovarian Cycle

The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle.  At puberty, GnRH secretion increases in both frequency and...
Oogenesis02:07

Oogenesis

In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
Ovarian Cycle01:27

Ovarian Cycle

The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle length...
Cushing Syndrome II: Pathophysiology01:19

Cushing Syndrome II: Pathophysiology

Cortisol production is normally governed by the hypothalamic–pituitary–adrenal (HPA) axis, which maintains hormonal balance through tightly regulated feedback mechanisms. Disruption of this regulatory system is central to the development of Cushing syndrome, whether the excess cortisol originates from external medications or internal pathology. Persistent cortisol elevation alters metabolism, immune function, and endocrine signaling, producing the characteristic clinical features of the...
Ovaries01:26

Ovaries

The ovaries are roughly the size of almonds and measure approximately 2 to 3 centimeters in length. These paired structures are situated within the pelvic region and are anchored by the mesovarium—a peritoneal extension that also connects them to the wider structure of the broad ligament. The support system extends to the suspensory ligament, housing blood and lymphatic vessels. In addition, the ovarian ligament tethers the ovaries to the uterus.
On the ovarian surface, a layer of cuboidal...
Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...

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Related Experiment Video

Updated: May 23, 2026

Evaluation of Hepatic Glucose Production in a Polycystic Ovary Syndrome Mouse Model
09:44

Evaluation of Hepatic Glucose Production in a Polycystic Ovary Syndrome Mouse Model

Published on: March 5, 2022

[Polycystic ovary syndrome].

H Mourikis1, J Zervas

  • 1Department of Psychiatry, University of Athens, "Eginition" Hospital, Athens, Greece.

Psychiatrike = Psychiatriki
|April 3, 2012
PubMed
Summary

Polycystic Ovary Syndrome (PCOS), a common endocrine disorder, is linked to psychiatric symptoms due to steroid deregulation. Recognizing these connections is crucial for diagnosing and treating women with PCOS.

Area of Science:

  • Endocrinology
  • Neuroscience
  • Psychiatry

Context:

  • Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine disorder affecting reproductive-aged women.
  • PCOS presents complex reproductive and metabolic issues with known links to psychiatric disorders.
  • Recent research focuses on the cellular level, particularly neurosteroids and their impact.

Purpose:

  • To explore the pathophysiological and clinical links between PCOS-related steroid dysregulation and psychiatric symptomatology.
  • To highlight the relevance of PCOS in various psychiatric conditions treated in medical practice.
  • To emphasize the psychological impact of PCOS on women's mental health and quality of life.

Summary:

  • Steroid deregulation in PCOS affects neurotransmitter systems and neuroplasticity, contributing to psychiatric symptoms.

More Related Videos

A Modified Technique for Inducing Polycystic Ovary Syndrome in Mice
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A Modified Technique for Inducing Polycystic Ovary Syndrome in Mice

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A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome
08:20

A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome

Published on: October 2, 2018

Related Experiment Videos

Last Updated: May 23, 2026

Evaluation of Hepatic Glucose Production in a Polycystic Ovary Syndrome Mouse Model
09:44

Evaluation of Hepatic Glucose Production in a Polycystic Ovary Syndrome Mouse Model

Published on: March 5, 2022

A Modified Technique for Inducing Polycystic Ovary Syndrome in Mice
04:49

A Modified Technique for Inducing Polycystic Ovary Syndrome in Mice

Published on: July 5, 2024

A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome
08:20

A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome

Published on: October 2, 2018

  • PCOS is associated with conditions such as bipolar disorder, depression, anxiety, cognitive, sleep, eating, and somatoform disorders.
  • Women with PCOS often experience depressive symptoms, anxiety, body image issues, and reduced quality of life.

    • Impact:

    • Clinicians should consider the psychiatric and psychological dimensions of PCOS for accurate diagnosis and effective treatment.
    • Understanding the interplay between PCOS and mental health can improve patient outcomes and therapeutic strategies.
    • This research underscores the importance of an integrated approach to managing PCOS, addressing both endocrine and psychiatric aspects.