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Related Experiment Video

Updated: May 23, 2026

An Intact Pericardium Ischemic Rodent Model

An Intact Pericardium Ischemic Rodent Model

Published on: September 2, 2021

Melioidotic pericardial effusion.

Thomas S Kuruvilla¹, Meena Dias, Uttam Udayan

¹Department of Microbiology, Father Muller Medical College, Mangalore, Karnataka, India. thomssk@yahoo.com

Indian Journal of Medical Sciences

|April 3, 2012

Summary

A rare case of purulent pericardial effusion caused by Burkholderia pseudomallei is presented. This infection can be misdiagnosed as tuberculosis pericarditis, especially in India.

Area of Science:

Microbiology
Infectious Diseases
Clinical Medicine

Background:

Tuberculosis (TB) is a leading cause of pericarditis globally.
Awareness of alternative pathogens is crucial for accurate diagnosis and treatment.
Purulent pericardial effusion requires prompt identification of the causative agent.

Observation:

A case of purulent pericardial effusion was identified.
The effusion sample was analyzed using automated blood culture and biochemical testing.
The causative organism was identified as Burkholderia pseudomallei.

Findings:

Burkholderia pseudomallei was confirmed as the cause of purulent pericardial effusion.
The identification was based on Gram stain, biochemical tests, and drug susceptibility.

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This represents a rare etiology of pericarditis.

Implications:

Clinicians and microbiologists in India should consider Burkholderia pseudomallei in cases of pericarditis.
Misdiagnosis as TB pericarditis can lead to delayed or inappropriate treatment.
Early and accurate identification of Burkholderia pseudomallei is vital for patient outcomes.