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Updated: May 23, 2026

Grossing of Non-neoplastic Globes, Including Fetal Eyes
Published on: May 30, 2025
US and MRI of pediatric ocular masses with histopathological correlation
Rachel C Brennan1, Matthew W Wilson, Sue Kaste
1Department of Oncology, St Jude Children's Research Hospital, MS 260, 262 Danny Thomas Place, Memphis, TN 38105, USA. rachel.brennan@stjude.org
Abstract:
We review our experience with unusual ocular pathologies, some mimicking retinoblastoma, that were referred to our institution during the past two decades. After presenting the imaging anatomy of the normal eye, we discuss pertinent clinical and pathological features, and illustrate the US and MRI appearance of retinoblastoma, medulloepithelioma, uveal melanoma, persistent fetal vasculature, Coats disease, corneal dermoid, retinal dysplasia and toxocara granuloma. Features useful in discriminating among these entities are emphasized.
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