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Related Concept Videos

Mass Analyzers: Overview01:13

Mass Analyzers: Overview

The mass analyzer is a crucial component of the mass spectrometer. In the ionization chamber, the vaporized sample is bombarded with a high-energy electron beam to generate a radical cation and further fragment into neutral molecules, radicals, and cations. A series of negatively charged accelerator plates accelerate the cations into the mass analyzer. The mass analyzer separates ions according to their mass-to-charge (m/z) ratios and then directs them to the detector. The common types of mass...
Atomic Force Microscopy01:08

Atomic Force Microscopy

Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...
Mass Analyzers: Common Types01:19

Mass Analyzers: Common Types

The quadrupole mass analyzer consists of four cylindrical metal rods arranged in a diamond carrying a DC voltage and a radio-frequency AC voltage. The motion of ions through the quadrupole depends on the field strength, causing only ions of a certain m/z to resonate successfully and strike the detector at a given field strength. Though the transmission rate for these analyzers is high, the exact elemental composition of the sample is not determined because of low resolution; however, they are...

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Related Experiment Video

Updated: May 23, 2026

High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements
08:50

High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements

Published on: May 12, 2023

A nanomechanical mass sensor with yoctogram resolution.

J Chaste1, A Eichler, J Moser

  • 1Catalan Institute of Nanotechnology, CIN2(ICN-CSIC), Campus de la UAB, 08193 Bellaterra, Barcelona, Spain.

Nature Nanotechnology
|April 3, 2012
PubMed
Summary
This summary is machine-generated.

Researchers developed a carbon nanotube resonator capable of detecting single proton masses. This ultrasensitive nanomechanical mass sensor achieved a resolution of 1.7 yoctograms (yg), enabling new applications in surface science and mass spectrometry.

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Area of Science:

  • Physics
  • Materials Science
  • Chemistry

Background:

  • Nanomechanical resonators are crucial for mass sensing applications, including weighing cells and biomolecules.
  • High mass resolution is essential for detecting minute quantities and studying surface phenomena.

Purpose of the Study:

  • To demonstrate mass sensing with unprecedented resolution using a carbon nanotube resonator.
  • To explore the capabilities of ultrasensitive nanotube resonators for detecting single molecules and measuring binding energies.

Main Methods:

  • Utilized a carbon nanotube resonator with a length of approximately 150 nm and a vibrational frequency near 2 GHz.
  • Performed mass sensing experiments to achieve a resolution of 1.7 yoctograms (yg), equivalent to the mass of a single proton.

Main Results:

  • Achieved a mass resolution of 1.7 yg, a new benchmark in nanomechanical sensing.
  • Successfully detected adsorption events of naphthalene molecules (C(10)H(8)).
  • Measured the binding energy of a single xenon atom on the nanotube surface.

Conclusions:

  • Ultrasensitive carbon nanotube resonators offer a powerful tool for high-resolution mass sensing.
  • These resonators have potential applications in advanced mass spectrometry, magnetometry, and surface science research.