[Perioperative renal function of patients with chronic renal diseases]

Perioperative renal function was studied in the patients with compensated renal failure whose values of BUN and serum Cr were above 30 and 2mg.dl-1 respectively, and those with chronic renal diseases whose values of BUN and serum Cr were normal. Serum and urine electrolyte, urea N, beta 2 microglobulin, Cr, Ccr, FENa and urine N-acetyl-beta-D-glucosaminidase were checked before, during and after operation for 2 weeks. Anesthesia mainly chosen was neuroleptanesthesia with vecuronium. In both groups, the function of glomeruli was not influenced during perioperative period. In both groups, during operation and 5 to 8 days after operation the value of FENa increased and returned to the preoperative value on the 14th postoperative day. The value of urine beta 2 microglobulin increased on the 5th postoperative day in both groups. During perioperative period renal tubular function was mainly influenced and returned to preoperative value 5 to 14 days after the operation. The perioperative care of the patients with chronic renal diseases including compensated renal failure is different from that of the patients with renal failure treated by hemodialysis.