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Appendicitis

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...

Appendicitis-I: Introduction

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...

Appendicitis-II: Diagnostic Studies and Management

Appendicitis-II: Diagnostic Studies and Management

Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...

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Related Experiment Video

Updated: May 23, 2026

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Published on: August 24, 2019

Primary appendiceal mucinous adenocarcinoma.

Prativa Kumari Behera¹, Pramod Kumar Rath, Rabiratna Panda

¹Ispat General Hospital, Rourkela, India.

The Indian Journal of Surgery

|April 3, 2012

Summary

Primary appendiceal adenocarcinoma is rare. This case highlights a mucinous adenocarcinoma misdiagnosed as acute appendicitis, underscoring the need for mandatory histological examination of all appendectomy specimens.

Keywords:

Appendicitis Appendix Biopsy Mucinous adenocarcinoma

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Area of Science:

Gastroenterology
Surgical Oncology
Pathology

Background:

Primary adenocarcinomas of the appendix are exceptionally rare malignancies.
Appendiceal neoplasms can present insidiously, often mimicking common appendiceal pathologies.

Purpose of the Study:

To report a case of primary mucinous adenocarcinoma of the appendix.
To emphasize the importance of histopathological examination in diagnosing rare appendiceal tumors.

Main Methods:

Case presentation of a 40-year-old female initially diagnosed with acute appendicitis.
Diagnostic workup included routine investigations and abdominal ultrasonography.
Appendectomy followed by histopathological examination of the specimen.
Completion right hemicolectomy performed as a secondary procedure.

Main Results:

Routine investigations and initial imaging were non-specific for malignancy.
Histopathological examination confirmed mucinous adenocarcinoma of the appendix.
The patient underwent a successful second-stage surgical resection.

Conclusions:

Primary appendiceal mucinous adenocarcinoma can be misdiagnosed as acute appendicitis.
Mandatory histopathological examination of all appendectomy specimens is crucial for accurate diagnosis and management.
Early detection through histology can prevent delayed treatment of rare appendiceal cancers.