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Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
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Larynx01:21

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Related Experiment Video

Updated: May 23, 2026

Assessment of the Efficacy of An Osteopathic Treatment in Infants with Biomechanical Impairments to Suckling
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Ankyloglossia and breastfeeding.

A Rowan-Legg

    Paediatrics & Child Health
    |April 3, 2012
    PubMed
    Summary

    Ankyloglossia, or tongue-tie, is a congenital condition with unclear links to infant breastfeeding issues. Current evidence does not support routine frenotomy, recommending it only when severe tongue-tie and breastfeeding problems are clearly linked.

    Area of Science:

    • Pediatrics
    • Neonatal Care
    • Surgical Anomalies

    Background:

    • Ankyloglossia (tongue-tie) is a congenital anomaly characterized by a short lingual frenulum.
    • The link between ankyloglossia and infant breastfeeding difficulties is controversial and lacks consistent evidence.
    • Current management guidelines are not based on robust clinical trials.

    Purpose of the Study:

    • To review the current evidence regarding ankyloglossia and its association with infant breastfeeding problems.
    • To evaluate the efficacy and indications for frenotomy in managing tongue-tie.
    • To provide recommendations for the management of ankyloglossia in infants.

    Main Methods:

    • Literature review of existing studies on ankyloglossia and breastfeeding.
    • Analysis of the evidence base for surgical intervention (frenotomy).
    Keywords:
    AnkyloglossiaBreastfeedingInfant

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  • Assessment of diagnostic criteria and management strategies.
  • Main Results:

    • Evidence linking ankyloglossia to breastfeeding problems is inconsistent.
    • Frenotomy, the surgical correction, is not currently recommended based on available data.
    • Clear identification of significant tongue-tie and major breastfeeding issues may warrant frenotomy by experienced clinicians.

    Conclusions:

    • Routine frenotomy for ankyloglossia is not supported by current evidence.
    • Frenotomy should be considered cautiously for severe cases with clearly identified breastfeeding problems.
    • Further high-quality, randomized controlled trials are needed to establish definitive management guidelines for infant tongue-tie.