Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 23, 2026

Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate (HoLEP).
06:04

Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate (HoLEP).

Published on: March 6, 2018

Benign prostatic hyperplasia: from bench to clinic.

Tag Keun Yoo1, Hee Ju Cho

  • 1Department of Urology, Eulji University School of Medicine, Seoul, Korea. ytk5202@eulji.ac.kr

Korean Journal of Urology
|April 3, 2012
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Interleukin-6 secreted by tumor-associated macrophages promotes proliferation and migration through JAK2/STAT3 signaling pathway in human prostate cancer cells.

Prostate international·2026
Same author

Reconsidering molecular pathways in giant benign prostatic hyperplasia: a potential strategy for an unmet challenge.

Expert review of clinical pharmacology·2026
Same author

A randomized, active-controlled, multicenter, phase 3 clinical trial to evaluate the efficacy and safety of GV1001 in patients with benign prostatic hyperplasia.

Prostate international·2025
Same author

Older age and low testosterone levels are independently associated with kidney stone prevalence in men: results from a large cross-sectional study.

International journal of impotence research·2025
Same author

Triple Silencing of HSP27, cFLIP, and CLU Genes Promotes the Sensitivity of Doxazosin-Induced Apoptosis in PC-3 Prostate Cancer Cells.

Medicines (Basel, Switzerland)·2024
Same author

Safety and efficacy of tamsulosin 0.4 mg as an initial dose in 1,219 Korean patients with moderate to severe lower urinary tract symptoms: data from a phase IV study.

Prostate international·2024

Benign prostatic hyperplasia (BPH) causes lower urinary tract symptoms (LUTS) in aging men. Current treatments focus on symptom management, with evolving medical and surgical options like alpha-blockers and laser therapies offering alternatives to traditional surgery.

Area of Science:

  • Urology
  • Geriatrics
  • Pharmacology

Background:

  • Benign prostatic hyperplasia (BPH) is a common condition in older men, leading to lower urinary tract symptoms (LUTS).
  • LUTS result from both mechanical and dynamic prostatic obstruction, with the exact etiology of BPH remaining unclear.
  • The financial and care implications of BPH necessitate a thorough understanding of its causes and effective management strategies.

Purpose of the Study:

  • To review current understanding of BPH etiology, including metabolic, inflammatory, hormonal, and lifestyle factors.
  • To explore evolving medical and surgical treatment options for BPH and LUTS.
  • To discuss the shift towards symptom-focused management and the changing role of traditional surgical interventions.

Main Methods:

  • Review of preclinical and clinical studies on BPH.
Keywords:
EtiologyLower urinary tract symptomsProstatic hyperplasiaTherapy

More Related Videos

Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia
08:38

Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia

Published on: August 28, 2013

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing
05:25

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing

Published on: August 14, 2019

Related Experiment Videos

Last Updated: May 23, 2026

Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate (HoLEP).
06:04

Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate (HoLEP).

Published on: March 6, 2018

Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia
08:38

Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia

Published on: August 28, 2013

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing
05:25

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing

Published on: August 14, 2019

  • Analysis of various etiological theories for benign prostatic enlargement and LUTS.
  • Evaluation of efficacy and safety profiles of existing and emerging BPH treatments.

    • Main Results:

    • Several factors, including metabolic syndrome, inflammation, and hormonal influences, are implicated in BPH development.
    • Alpha-antagonists (e.g., alfuzosin, tamsulosin) and newer agents (silodosin, naftopidil, PDE5 inhibitors) demonstrate efficacy in managing LUTS.
    • Minimally invasive surgical options like laser prostatectomy offer alternatives to transurethral resection of the prostate (TURP), with TURP's gold standard status evolving.

    Conclusions:

    • BPH management is increasingly focused on symptom relief due to incomplete correlation between prostate size and LUTS.
    • A range of medical therapies, including alpha-blockers and phosphodiesterase 5 inhibitors, provide effective treatment options.
    • Advancements in surgical techniques, particularly laser therapies, are refining BPH treatment, offering improved safety profiles and alternatives to TURP.