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Related Experiment Video

Updated: May 23, 2026

Injections of Lipopolysaccharide into Mice to Mimic Entrance of Microbial-derived Products After Intestinal Barrier Breach

Injections of Lipopolysaccharide into Mice to Mimic Entrance of Microbial-derived Products After Intestinal Barrier Breach

Published on: May 2, 2018

Immunological responses to gut bacteria.

Julia M Green-Johnson¹

¹University of Ontario Institute of Technology, Faculty of Science, 2000 Simcoe St, Oshawa, ON, Canada L1H 7K4. Julia.Green-Johnson@uoit.ca

Journal of AOAC International

|April 4, 2012

Summary

This summary is machine-generated.

The gut microbiota profoundly influences the immune system and host defenses. This review explores the complex, bidirectional relationship between gut microbes and the host immune system.

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An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions

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Injections of Lipopolysaccharide into Mice to Mimic Entrance of Microbial-derived Products After Intestinal Barrier Breach

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Published on: May 2, 2018

An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions

An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions

Published on: June 30, 2021

Area of Science:

Immunology
Microbiology
Gastroenterology

Background:

The gut microbiota plays a crucial role in host health, particularly in modulating immune responses.
Host-microbe interactions are complex and dynamic, impacting various physiological processes.

Purpose of the Study:

To review the adaptive and innate immune responses to the gut microbiota.
To highlight the bidirectional nature of host-microbe interactions.

Main Methods:

Literature review of current research on gut microbiota and host immunity.
Synthesis of findings on immune cell activation and signaling pathways.

Main Results:

Gut microbiota extensively shapes both innate and adaptive immunity.
Immune responses are tailored to specific microbial communities and their metabolites.

Conclusions:

Understanding host-microbe interactions is vital for immune system regulation.
Targeting the gut microbiota offers therapeutic potential for immune-related diseases.