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Improving potencies and properties of CD4 down-modulating CADA analogs

Thomas W Bell1, Violeta G Demillo, Dominique Schols

  • 1University of Nevada, Department of Chemistry, Reno, Nevada 89557-0216, USA. twb@unr.edu

Expert Opinion on Drug Discovery
|April 4, 2012
PubMed
Summary

Researchers are developing CADA analogs, a novel class of small molecules, to inhibit HIV replication by down-modulating CD4 cell surface receptors. Future work aims to enhance potency and drug-like properties for improved HIV therapeutics.

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