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Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction
Published on: June 29, 2013
[To born small for gestational age may depend on the growth curve used]
A Ayerza Casas1, G Rodríguez Martínez, M P Samper Villagrasa
1Hospital Clínico Universitario Lozano Blesa, Zaragoza, España.
Insights
Different intrauterine growth standards significantly impact the identification of newborns small for gestational age (SGA). The Lubchenco charts identify fewer SGA infants compared to other standards, highlighting the importance of selecting appropriate growth curves for accurate risk assessment.
Area of Science:
- Neonatalogy
- Pediatric Endocrinology
- Public Health
Context:
- Accurate assessment of intrauterine growth is crucial for identifying newborns at risk.
- Population-specific growth standards are essential for evaluating infant well-being and nutritional status.
- Variations in diagnostic criteria can affect the identification rates of small for gestational age (SGA) infants.
Purpose:
- To analyze the differences in the number of small for gestational age (SGA) newborns identified using various population standards.
- To evaluate the suitability of different intrauterine growth charts for a Caucasian newborn population.
- To compare the performance of Olsen, Lubchenco, Delgado, and Carrascosa growth standards in identifying SGA infants.
Summary:
- A cross-sectional study of 4,486 Caucasian newborns (35-41 weeks gestation) assessed weight and length against four different growth standards.
- The Lubchenco curves showed significantly lower 10th percentile values for higher gestational ages and identified fewer SGA infants compared to Olsen, Delgado, and Carrascosa standards.
- The percentage of SGA infants identified ranged from 1.7% to 14%, depending on the standard, sex, and gestational age, with Lubchenco charts demonstrating a poor fit for this population.
Impact:
- The choice of intrauterine growth standard significantly influences the classification of SGA infants.
- Lubchenco charts are less suitable for this population, potentially leading to underdiagnosis of SGA.
- Accurate SGA identification is vital for timely intervention and managing short- and long-term health risks in newborns.
Introduction And Objective:
Population standards of intrauterine growth are necessary to evaluate if the newborn has grown well, if their nutritional conditions are appropriate and to identify groups at risk as those small for gestational age (SGA). Differences in the number of SGA newborns identified, depending on the standard applied, have been analyzed in this study.
Material And Methods:
Cross-sectional study conducted in 4,486 Caucasian newborns (2,361 boys and 2,125 girls), born between 35 and 41 weeks. Weight and length valuation was performed following the standard methodology. Percentage of children under the 10(th) percentile for weight and length was calculated depending on the standard used (Olsen et al. 2010, Lubchenco et al. 1966, Delgado et al. 1996, Carrascosa et al. 2008), being diagnosed of SGA.
Results:
Weight and length were significantly higher in boys than in girls at all ages. 10(th) percentile values defined for every gestational age are globally similar among the different standards and our population, with the clear exception of Lubchenco curves whose 10(th) percentile values are even 300 g. lower for the newborns at the highest gestational ages. Lubchenco charts do not fit the pattern of intrauterine growth of our population and identify a smaller number of SGA. The percentage of SGA of our sample ranged between 1.7% and 14% in depending on the standard, sex and gestational age considered.
Conclusion:
The number of children classified as SGA is different according to each standard used. Lubchenco charts identify a smaller number of SGA than the others. The rest of curves show similar values and seem to be well adapted for our population. The correct identification of SGA will allow a better assessment of short and long-term risks of these newborns.
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