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VDRL test and its interpretation
Surajit Nayak1, Basanti Acharjya
1Department of Skin and VD, MKCG Medical College and Hospital, Berhampur, Orissa, India. surajitnyk@yahoo.co.in
Abstract:
Venereal disease research laboratory (VDRL) test is a nontreponemal test, used for screening of syphilis due to its simplicity, sensitivity and low cost. Prozone phenomenon and biological false positive (BFP) reaction are two shortcomings of this test. Quantitative estimation of VDRL is essential in treatment evaluation. CSF VDRL test is very specific for neurosyphilis though its sensitivity is low. Interpretation of VDRL in HIV infection is incompletely understood.
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