Related Experiment Video
Updated: May 23, 2026
11:30
A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro
Published on: June 2, 2022
Myocardial calcinosis in chronic renal failure
Ashley E Kempf1, Maryam Golshan Momeni, Farhood Saremi
1Department of Radiological Sciences, University of California, Orange, CA, USA.
Journal of Radiology Case Reports
|April 4, 2012
Summary
End-stage renal disease can cause extensive cardiac calcification, affecting heart valves and potentially leading to fatal arrhythmias. This case highlights a rare but serious complication in a young patient with a history of kidney disease.
Area of Science:
- Cardiology
- Nephrology
- Radiology
Background:
- End-stage renal disease (ESRD) is associated with significant cardiovascular complications.
- Cardiac calcification is a known but under-recognized manifestation in ESRD patients.
- Renal transplant rejection can exacerbate underlying conditions.
Purpose of the Study:
- To present a rare case of diffuse endocardial and myocardial calcification in an 18-year-old male with ESRD and a rejected renal transplant.
- To highlight the potential link between ESRD, cardiac calcification, and adverse cardiac events.
Main Methods:
- Case report of an 18-year-old male.
- Diagnostic workup included echocardiogram and non-contrast computed tomography (CT) of the chest.
Main Results:
- Echocardiogram and CT revealed diffuse endocardial and myocardial calcifications.
- The patient had a history of end-stage renal disease and a rejected renal transplant.
Conclusions:
- Extensive cardiac calcification is a rare but critical complication in patients with end-stage renal disease.
- This condition may lead to severe cardiac issues, including valvular dysfunction and fatal arrhythmias.
- Early recognition and management are crucial for patients with ESRD and cardiac calcification.
Related Concept Videos
01:18Chronic Kidney Disease IV: Nursing Management
Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of fluid...
01:28Chronic Kidney Disease III: Interprofessional Care
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
01:24Chronic Kidney Disease II: Clinical Manifestations
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
01:29Cardiomyopathy IV: Restrictive Cardiomyopathy
Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
01:25Chronic Kidney Disease I: Introduction
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
01:29Acute Kidney Injury II: Pathophysiology
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...