Related Experiment Video
Updated: May 23, 2026
10:33
Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis
Published on: December 17, 2021
Kikuchi-fujimoto disease with bilateral uveitis.
Hope R Garner1, Hilary E Fazzone, Daniel E Meltzer
1Department of Radiology, St. Luke's-Roosevelt Hospital Center, New York, NY, USA.
Journal of Radiology Case Reports
|April 4, 2012
Summary
Kikuchi-Fujimoto disease (KFD), a rare condition causing lymphadenitis and fever, can present with unusual ocular symptoms. This case highlights KFD associated with bilateral anterior uveitis and MRI findings.
Area of Science:
- Ophthalmology
- Pathology
- Radiology
Background:
- Kikuchi-Fujimoto disease (KFD), or histiocytic necrotizing lymphadenitis, is a rare condition typically presenting with lymphadenitis and fever.
- KFD is often linked to infectious agents, particularly viruses, and systemic inflammatory processes.
Purpose of the Study:
- To report a rare case of Kikuchi-Fujimoto disease (KFD) presenting with bilateral anterior uveitis.
- To correlate the clinical ocular findings with magnetic resonance imaging (MRI) findings in KFD.
Main Methods:
- Case report detailing clinical presentation and diagnostic workup.
- Review of medical literature for similar presentations of KFD with ocular manifestations.
- Magnetic resonance imaging (MRI) of the orbits and brain.
Main Results:
- The patient presented with symptoms consistent with Kikuchi-Fujimoto disease and bilateral anterior uveitis.
- Magnetic resonance imaging (MRI) revealed specific findings associated with the ocular inflammation.
- Literature review confirmed the rarity of ocular involvement in KFD.
Conclusions:
- Kikuchi-Fujimoto disease (KFD) can manifest with rare ocular complications such as bilateral anterior uveitis.
- Magnetic resonance imaging (MRI) can provide valuable insights into the extent and nature of ocular involvement in KFD.
- This case underscores the importance of considering KFD in the differential diagnosis of unexplained anterior uveitis, especially when accompanied by systemic symptoms.
Related Concept Videos
01:25Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
01:20Inflammatory Bowel Disease II: Ulcerative Colitis
Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal BarrierA...
01:25Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...