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Updated: May 23, 2026
03:57
Transmesenteric Laparoscopic Pyeloplasty in Trendelenburg Position for Horseshoe Kidney with Hydronephrosis
Published on: July 8, 2025
Gardner syndrome complicated with hydronephrosis. A case report
Paolo Cabassa1, Mario Morone, Enza Gatti
1Department of Radiology Spedali Civili, Brescia University, Brescia, Italy.
Journal of Radiology Case Reports
|April 4, 2012
Summary
Gardner syndrome, a genetic disorder, can manifest as rectal cancer relapse with desmoid tumors and osteomas. This case highlights potential complications like ureteral obstruction from tumor recurrence.
Area of Science:
- Genetics
- Oncology
- Gastroenterology
Background:
- Gardner syndrome is an autosomal dominant disorder.
- It is characterized by colonic polyposis, osteomas, and soft tissue tumors.
- Adenocarcinoma of the rectum can occur in patients with Gardner syndrome.
Purpose of the Study:
- To present a case of rectal adenocarcinoma relapse in a patient diagnosed with Gardner syndrome.
- To illustrate the complex presentation and management of Gardner syndrome.
- To highlight potential complications of recurrent disease.
Main Methods:
- Case report presentation.
- Computed Tomography (CT) staging for diagnosis and follow-up.
- Surgical intervention and chemotherapy for treatment.
Main Results:
- A male patient presented with rectal adenocarcinoma relapse.
- CT staging revealed multiple desmoid tumors and osteomas, confirming Gardner syndrome.
- Follow-up CT demonstrated disease relapse with hydronephrosis due to ureteral compression.
Conclusions:
- Gardner syndrome requires vigilant monitoring for malignant and benign neoplastic recurrence.
- Desmoid tumors and osteomas are key features in this genetic disorder.
- Ureteral compression leading to hydronephrosis is a potential severe complication of recurrent disease.
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