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Updated: May 23, 2026

A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
Pediatric holohemispheric developmental venous anomaly: definitive characterization by 3D susceptibility weighted
Michael A Casey1, Sourabh Lahoti, Ajeet Gordhan
1Advocate Bromenn Neurosurgery, Normal, Illinois, USA.
Abstract:
We present a case of an incidentally discovered holohemispheric developmental venous anomaly (DVA) in a 12 year old, conclusively characterized by 3D T2* multi-echo sequence susceptibility weighted angiographic imaging (SWAN). For the evaluation of head trauma, abnormal right intraparenchymal and periventricular vascularity was identified by a non contrast head CT scan. Conventional MRI sequences revealed prominent veins with findings suspicious of a DVA. A definitive diagnosis was made by identifying angiographic features typical for DVA by augmented susceptibility weighted angiographic imaging. Using this sequence the entire hemispheric extent of the anomaly without complicating features was definitively characterized, negating the need for a catheter based angiographic study. A holohemispheric DVA in a child to our knowledge has not been previously described.
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