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Updated: May 23, 2026

18F-Labeling of Radiotracers Functionalized with a Silicon Fluoride Acceptor (SiFA) for Positron Emission Tomography
Published on: January 11, 2020
Particle disease on fluoride-18 (NaF) PET/CT imaging
Jonathan Kuo1, Cameron Foster, David Shelton
1Department of Radiology, University of California, Davis Medical Center, Sacramento, CA 95817, USA. Jonathan.kuo@ucdmc.ucdavis.edu
Abstract:
Particle disease is a loss of bone that commonly occurs about five years after arthroplasty. The cause is secondary to microabrasive wear and shedding of any portion of the prosthesis, and the microscopic foreign bodies activate inflammation which can lead to pain. This report describes the imaging findings of an 80-year-old female with particle disease detected with 18F-fluoride PET/CT.
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