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Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation
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Interleukin 2 gene polymorphisms are associated with non-Hodgkin lymphoma

Haihan Song1, Lei Chen, Zhanshan Cha

  • 1Department of Internal Medicine, Emergency Center, Shanghai East Hospital, Tongji University, Shanghai, China.

DNA and Cell Biology
|April 5, 2012
PubMed
Summary

Interleukin-2 (IL-2) gene polymorphisms, specifically the -330TG and -330GG genotypes, are associated with increased susceptibility to Non-Hodgkin lymphoma (NHL) in the Chinese population. The -330G/+114T haplotype also showed a higher prevalence in NHL cases, suggesting IL-2 gene variations as potential risk factors.

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