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Updated: May 23, 2026

High Frequency Ultrasound for the Analysis of Fetal and Placental Development In Vivo
Published on: November 8, 2018
Placental location and newborn weight.
Karthika Devarajan1, Sari Kives1, Joel G Ray2
1Department of Obstetrics and Gynecology, University of Toronto, Toronto ON.
Placental location, whether lateral or central, did not significantly impact newborn weight or adverse pregnancy outcomes like small for gestational age births or hypertensive disorders.
Area of Science:
- Obstetrics and Gynecology
- Perinatal Medicine
- Fetal Development
Background:
- Placental location is hypothesized to influence fetal growth and pregnancy complications.
- Previous research suggests a potential link between placental positioning and perinatal outcomes.
Purpose of the Study:
- To investigate the association between placental location (lateral vs. central/fundal) and newborn birth weight.
- To assess the relationship between placental location and the incidence of small for gestational age (SGA) and pregnancy-induced hypertension.
Main Methods:
- Retrospective cohort study of 796 singleton births at ≥ 37 weeks' gestation.
- Placental location determined by second-trimester ultrasound (16-24 weeks' gestation).
- Logistic regression analysis adjusted for multiple maternal and infant factors.
Main Results:
- No significant difference in mean birth weight between lateral (3298 g) and central/fundal (3352 g) placentas.
- Adjusted odds ratios for SGA (0.81) and hypertensive disorders (0.62) were not statistically significant for lateral placentas compared to central/fundal.
Conclusions:
- Placental location, categorized as lateral or central/fundal, showed no association with newborn birth weight.
- Placental location was not found to be a significant predictor of small for gestational age or pregnancy-induced hypertension in this cohort.
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