Related Experiment Video
Updated: May 23, 2026

Using the Activity-based Anorexia Rodent Model to Study the Neurobiological Basis of Anorexia Nervosa
Published on: October 22, 2015
Emotion and eating disorder symptoms in patients with anorexia nervosa: an experimental study
Jennifer E Wildes1, Marsha D Marcus, Ashley C Bright
1Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. wildesje@upmc.edu
Objective:
To evaluate the effect of negative emotion on self-reported eating disorder symptoms and objectively-measured eating behavior in patients with anorexia nervosa (AN).
Method:
Twenty-eight females with AN were randomized to a negative or neutral mood induction followed by a test meal. Participants completed assessments one week before the experimental session, before (pretest) and after (posttest) the mood induction, and after the test meal.
Results:
Participants in the negative emotion condition had an increase in negative affect from pretest to posttest that was accompanied by significantly greater increases in self-reported eating disorder symptoms than were exhibited by participants in the neutral emotion condition, who had no increase in negative affect. There was no effect of emotion condition on eating behavior.
Discussion:
Results suggest that negative emotions influence the expression of cognitive eating disorder symptoms in individuals with AN, which may have implications for the identification of treatment targets.
Related Concept Videos
Anorexia Nervosa
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
Bulimia Nervosa
Binge Eating Disorders

