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A diketopyrrolopyrrole-based colorimetric and fluorescent probe for cyanide detection

Young-Hwan Jeong1, Chi-Hwa Lee, Woo-Dong Jang

  • 1Department of Chemistry, College of Science, Yonsei University, 262 Seongsanno, Seodaemun-gu, Seoul 120-749, Korea.

Chemistry, an Asian Journal
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Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...