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Related Concept Videos

Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
Spongy Bone01:09

Spongy Bone

All bones comprise an outer layer of compact bone, and an interior made up of spongy bone tissue, also called cancellous or trabecular bone. In long bones, spongy bone tissue is mainly found in the interior of the epiphyses (broad ends of the bone).
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...
Bone Markings01:26

Bone Markings

Bones have various surface features that help form joints and attach to other soft tissues. Depending on the function, bone markings are categorized into articulating projections, processes for attachment, depressions, and openings.
Articulating Projections
Articulating projections are found where two bones meet to form a joint. These structures are usually found at the ends of bones. The largest articulation is a rounded projection called the head, supported by a narrow neck at the ends of...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Compact Bone01:27

Compact Bone

Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
Gross Anatomy of Bone01:17

Gross Anatomy of Bone

The two main features of a long bone are the diaphysis and the epiphysis.
The diaphysis is the tubular shaft that runs between the proximal and distal ends of the bone. The walls of the diaphysis are composed of dense and hard compact bone made of numerous osteons — the functional unit of the compact bone. The hollow region in the diaphysis is called the medullary cavity, which harbors the bone marrow. In infants and children, this marrow cavity is filled with red marrow, whereas in adults, it...

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Related Experiment Videos

Aneurysmal bone cyst.

Timothy B Rapp1, James P Ward, Michael J Alaia

  • 1Department of Orthopaedic Surgery, NYU Hospital for Joint Diseases, New York, NY, USA.

The Journal of the American Academy of Orthopaedic Surgeons
|April 5, 2012
PubMed
Summary
This summary is machine-generated.

Aneurysmal bone cysts are rare bone tumors typically found near the knee in young individuals. Treatment involves surgical removal and bone grafting, with a low recurrence rate after proper management.

Related Experiment Videos

Area of Science:

  • Orthopedics
  • Skeletal Oncology
  • Pathology

Background:

  • Aneurysmal bone cysts (ABCs) are uncommon skeletal neoplasms.
  • They predominantly affect individuals in their first two decades of life.
  • ABCs can occur in any bone, though they are most frequent around the knee.

Purpose of the Study:

  • To review the pathogenesis, clinical presentation, diagnostic imaging, histopathology, differential diagnoses, and management of aneurysmal bone cysts.
  • To highlight current treatment strategies and their efficacy.

Main Methods:

  • Review of radiographic and MRI findings characteristic of ABCs.
  • Histopathological examination revealing blood-filled spaces within fibrous stroma.
  • Comparison with differential diagnoses like telangiectatic osteosarcoma and giant cell tumor.

Main Results:

  • Radiographically, ABCs present as lucent lesions, often with fluid-fluid levels on MRI.
  • Histology shows vascular spaces within fibrous tissue.
  • Effective treatments include curettage with bone grafting, with options like cryotherapy and sclerotherapy.

Conclusions:

  • Aneurysmal bone cysts require careful diagnosis due to their varied presentation.
  • Surgical curettage and bone grafting are the primary treatment modalities.
  • While recurrence is uncommon, multiple interventions may be necessary for complete eradication.