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Updated: May 23, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Published on: June 12, 2021
Endoscopic evaluation and management of gastrointestinal bleeding in patients with ventricular assist devices
Marty M Meyer1, Scott D Young, Benjamin Sun
1Division of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Medical Center, Columbus, OH 43210, USA.
Insights
Diagnosing gastrointestinal bleeding (GIB) in ventricular assist device (VAD) patients is crucial. Endoscopic evaluations, including video capsule endoscopy, are safe and effective for identifying bleeding sources in VAD recipients.
Area of Science:
- Cardiology
- Gastroenterology
- Medical Devices
Background:
- Gastrointestinal bleeding (GIB) is a known complication in patients with ventricular assist devices (VADs).
- The optimal diagnostic strategies for GIB in this population remain unclear.
Purpose of the Study:
- To determine the diagnostic yield and safety of various endoscopic procedures for evaluating GIB in VAD patients.
- To explore the etiology of GIB in patients with VADs.
Main Methods:
- Retrospective review of VAD patients experiencing overt GIB between April 2000 and July 2008.
- Evaluation of endoscopic procedures including EGD, colonoscopy, balloon-assisted enteroscopy, and video capsule endoscopy (VCE).
Main Results:
- Thirty-six bleeding episodes in 20 patients were analyzed.
- Endoscopic evaluations successfully identified the GIB site in 88.9% and the etiology in 83.3% of cases.
- Video capsule endoscopy showed a high yield (80%) in identifying GIB etiology, with successful endoscopic intervention in 8/9 attempts and no reported adverse events.
Conclusions:
- Upper endoscopy, lower endoscopy, balloon-assisted enteroscopy, and VCE are safe and effective diagnostic tools for GIB in VAD patients.
- Standardized protocols are recommended for optimizing endoscopic evaluation and intervention in VAD patients with GIB.
Abstract:
The optimal diagnostic approach and yield for gastrointestinal bleeding (GIB) in patients with ventricular assist devices (VAD) are unknown. We explored the etiology of bleeding and yield of upper and lower endoscopy, balloon-assisted enteroscopy, and video capsule endoscopy in the evaluation of GIB in patients with VADs. Methods. All VAD patients with overt gastrointestinal bleeding and drop in hematocrit from April 1, 2000 to July 31, 2008 were retrospectively reviewed. The endoscopic evaluation of each episode was recorded. Overall yield of EGD, colonoscopy, balloon-assisted, and video capsule endoscopy were evaluated. Results. Thirty-six bleeding episodes occurred involving 20 patients. The site of GIB was identified in 32/36 episodes (88.9%), and the etiology of bleeding was determined in 30/36 cases (83.3%). Five VAD patients underwent VCE. The VCE exams demonstrated a high yield with 80% of exams identifying the etiology of GIB. Endoscopic intervention was successful in 8/9 attempts. No adverse events were recorded. Two patients required surgical intervention for GIB. Conclusion. Upper, lower, video capsule, and balloon-assisted enteroscopies are safe and demonstrate a high yield in the investigation of gastrointestinal bleeding in VAD patients. Medical centers caring for VAD patients should employ a standardized protocol to optimize endoscopic evaluation and intervention.
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