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Updated: May 23, 2026

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients
Published on: March 1, 2024
Neurological Disorders in Primary Sjögren's Syndrome
Gabriel J Tobón1, Jacques-Olivier Pers, Valérie Devauchelle-Pensec
1EA Immunologie et Pathologie, Université de Bretagne Occidentale et Centre Hospitalier Universitaire de Brest, BP 824, F2969 Brest, France.
Abstract:
Sjögren's syndrome is an autoimmune disease characterized by an autoimmune exocrinopathy involving mainly salivary and lacrimal glands. The histopathological hallmark is periductal lymphocytic infiltration of the exocrine glands, resulting in loss of their secretory function. Several systemic manifestations may be found in patients with Sjögren's syndrome including neurological disorders. Neurological involvement ranges from 0 to 70% among various series and may present with central nervous system and/or peripheral nervous system involvement. This paper endeavors to review the main clinical neurological manifestations in Sjögren syndrome, the physiopathology, and their therapeutic response.
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