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Updated: May 23, 2026

Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography

Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography

Published on: April 4, 2012

Recent advances in obesity: genetics and beyond.

Wai W Cheung¹, Peizhong Mao

¹Division of Pediatric Nephrology, Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA.

ISRN Endocrinology

|April 5, 2012

Summary

Obesity, a complex heritable trait influenced by genes and lifestyle, is rising globally. Genetic research identifies key hormones and brain pathways involved in appetite regulation, offering new therapeutic targets for this epidemic.

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Multidisciplinary Approach to Obesity Management: A Case Report

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Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography

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Multidisciplinary Approach to Obesity Management: A Case Report

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Area of Science:

Genetics
Epidemiology
Neuroscience

Background:

Obesity is a growing global health crisis with significant economic impact.
It is a heritable trait influenced by multiple genes and lifestyle factors.
Hormones and neurotransmitters regulating appetite and energy expenditure are implicated.

Purpose of the Study:

To review recent advances in the genetics of obesity.
To highlight established genetic loci influencing obesity.
To explore potential therapeutic strategies based on genetic insights.

Main Methods:

Genetic epidemiological approaches.
Review of recent scientific literature.
Analysis of established and newly identified genetic loci.

Main Results:

Identification of multiple genes and loci associated with obesity.
Understanding the role of hormones like leptin, CART, and ghrelin.
Emerging links between obesity and central nervous system disorders.

Conclusions:

Genetic factors play a crucial role in obesity development.
Understanding these genetic underpinnings can lead to novel treatments.
Further research into genetic loci is vital for combating the obesity epidemic.